dearJulius.com Write For Us

Researchers testing needle-free flu vaccine

SHARE:


By Serena Gordon, HealthDay News

Instead of visiting the doctor each fall, sitting in a waiting room filled with the sniffling, sneezing masses -- what if you could just slap on a flu vaccine "patch" sent in the mail?

That's the vision of researchers who've developed and conducted early tests on an injection-free vaccine that looks like a Band-Aid you place on your arm.

Their initial hope is to create such a vaccine that would allow for a rapid public health response in case of a pandemic flu.

"If there's a pandemic flu, the last thing you want is for people to be coughing on each other while they're waiting for a flu shot," said the study's lead author, Darrick Carter.

"The new vaccine uses a combination of three technologies, and was designed quite specifically to be used by the person receiving the vaccine. It could be sent through the mail, and you could put it on and protect yourself," said Carter. He's vice president of the Infectious Diseases Research Institute in Seattle.

Microneedles on the patch deliver the vaccine. "Mostly, when we get injured, we scrape ourselves or get a superficial wound, and much of the immune system lays on the surface of the skin to respond," Carter said, explaining why it isn't necessary to have an intramuscular injection.

Another component of the vaccine is a new type of antigen -- the substance that causes the immune system to produce protective antibodies. Carter said another company provided this component. It uses reprogrammed plant cells to produce virus-like particles.

The final component is an adjuvant -- a substance to boost the effectiveness of the vaccine.

The researchers tested a liquid form of the vaccine and the adjuvant on ferrets. A single vaccine fully protected the animals, they said.

They also gave the liquid form of the adjuvant and vaccine to 100 humans to test the vaccine's safety. There were no significant side effects. In addition, those given the vaccine showed a stronger immune response. However, this study wasn't designed to test how effective the vaccine was in humans.

"This is a clinical proof of concept study," Carter said. The researchers hope to get additional funding to move forward with the next phase of human trials. If all goes well, Carter said it might be possible to have this vaccine approved in five years or so.

Dr. David Davenport, director of infection prevention at Borgess Medical Center in Kalamazoo, Mich., said this could be a "game-changer." He was not involved with the study.

"Egg-based vaccines are incredibly antiquated and we have to move away from that," Davenport said. "The egg-based vaccine takes way too long [to manufacture], sometimes six months or longer. If we had a major epidemic, we need the ability to rapidly scale up, and a plant-based vaccine could take three months or less."

Plus, Davenport said, sending a vaccine through the mail for people to self-administer "could get high numbers of people vaccinated." Currently, fewer than half of Americans get an annual flu shot, the U.S. Centers for Disease Control and Prevention estimates.

Results of the ferret and early human trials were published Sept. 12 in the journal Science Advances.

More information
The U.S. Centers for Disease Control and Prevention has more advice on preventing the flu.

COMMENTS



Note: If you think this story need more information or correction, feel free to comment below your opinion and reaction.
Like & Follow to Stay Updated ...

Name

Body & Mind,3,Fitness,20,Health,1450,Weight Loss,3,Wellness,2,
ltr
item
Health - U.S. Daily News: Researchers testing needle-free flu vaccine
Researchers testing needle-free flu vaccine
https://2.bp.blogspot.com/-c1uaasUmKE8/W5oWITeBL5I/AAAAAAAA-Nw/HqP6CV3uF80wHajj20r9xo8RW7oMe4-PQCLcBGAs/s1600/1.jpg
https://2.bp.blogspot.com/-c1uaasUmKE8/W5oWITeBL5I/AAAAAAAA-Nw/HqP6CV3uF80wHajj20r9xo8RW7oMe4-PQCLcBGAs/s72-c/1.jpg
Health - U.S. Daily News
https://health.dailynews.us.com/2018/09/researchers-testing-needle-free-flu.html
https://health.dailynews.us.com/
https://health.dailynews.us.com/
https://health.dailynews.us.com/2018/09/researchers-testing-needle-free-flu.html
true
6734990777582388991
UTF-8
Loaded All Posts Not found any posts VIEW ALL Read More Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share. STEP 2: Click the link you shared to unlock Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy