dearJulius.com Write For Us

Blood biomarker may detect some types of autism

SHARE:

A metabolic panel can detect autism spectrum disorder in some children, potentially paving the way for a biomarker test. Photo by PhotoUG/Shutterstock

By Allen Cone, UPI

Researchers have identified a metabolic way to detect autism spectrum disorder in some children, potentially paving the way for a biomarker blood test.

Investigators at the University of California Davis and NeuroPointDX, a division of Stemina Biomarker Discovery, conducted the Children's Autism Metabolome Project, or CAMP, which is one of the largest studies of its kind. UC Davis' Medical Investigation of Neurodevelopmental Disorders, or MIND, examines neurodevelopmental disorders.

A study of the efficacy of the blood test, which was published Thursday in Biological Psychiatry, was able to detect about 16.7 percent of children with autism spectrum disorder.

Autism, which develops in childhood and continues through adulthood, is a neurological and developmental disorder that is prevalent in 1 in 59 children, the Centers for Disease Control and Prevention found in tracking 11 communities across the country.

"The long-term vision is, once we've been able to analyze all the data from CAMP, we would have a series of panels," senior author David G. Amaral, founding director of research at the MIND Institute, said in a press release. "Each of these would be able to detect a subset of kids with autism. Ultimately, metabolomics may be able to identify most children with autism."

No biomarker tests now exist to detect ASD. Instead, children are diagnosed based on their altered behaviors, which often aren't seen until they are 2-4 years old.

"Families often experience long waits to receive a definitive diagnosis due to the paucity of trained clinicians able to perform diagnostic assessment," the researchers wrote.

Researchers found autism can be detected in metabolome, molecules that remain after larger molecules have been broken down or metabolized. With metabolomics, genetic and environmental contributions to the development of autism can be monitored.

"By the time you're getting to metabolomics, you're looking at how the body is working, not just the genes it has," Amaral said.

In the study, blood samples were collected from 1,100 children, including about two-thirds having been diagnosed with ASD, between 18 months and 4 years old, at eight locations in the United States.

Researchers compared blood metabolites -- specifically, amino acids -- in 516 kids children with ASD and 164 with typical development.

Nearly 17 percent of the ASD children had unique concentrations of specific amino acids in their blood.

"It is unlikely that a single marker will detect all autism," Amaral said. "The hope is that we will be able to generate a panel of biomarkers that will detect a large proportion of people at risk. Moreover, this approach highlights metabolic pathways that may be targets of intervention."

COMMENTS



Note: If you think this story need more information or correction, feel free to comment below your opinion and reaction.
Like & Follow to Stay Updated ...

Name

Body & Mind,3,Fitness,20,Health,1450,Weight Loss,3,Wellness,2,
ltr
item
Health - U.S. Daily News: Blood biomarker may detect some types of autism
Blood biomarker may detect some types of autism
https://4.bp.blogspot.com/-Dl0a5Khaqak/W5N8Ed25fZI/AAAAAAAA9CE/zFM8d8-xOl0a7d12lVVRbV7jmzBPLBjQgCEwYBhgL/s1600/3.jpg
https://4.bp.blogspot.com/-Dl0a5Khaqak/W5N8Ed25fZI/AAAAAAAA9CE/zFM8d8-xOl0a7d12lVVRbV7jmzBPLBjQgCEwYBhgL/s72-c/3.jpg
Health - U.S. Daily News
https://health.dailynews.us.com/2018/09/blood-biomarker-may-detect-some-types.html
https://health.dailynews.us.com/
https://health.dailynews.us.com/
https://health.dailynews.us.com/2018/09/blood-biomarker-may-detect-some-types.html
true
6734990777582388991
UTF-8
Loaded All Posts Not found any posts VIEW ALL Read More Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share. STEP 2: Click the link you shared to unlock Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy