dearJulius.com Write For Us

Sounds waves may improve liquid biopsies for cancer

SHARE:

Researchers have developed a contact-free method of separating stray tumor cells in the bloodstream using the device pictured. Photo courtesy of Duke University

By Brooke Baitinger, UPI

Scientists have developed a method for separating circulating tumor cells, or CTCs, from blood samples quickly, which they say could help speed cancer diagnosis.

[post_ads]In a new study, published this week in the journal Small, scientists from Duke University, MIT and Nanyang Technological University in Singapore demonstrate a platform based on sound waves to separate CTCs from a 7.5-ml vial of blood. The process took less than an hour and succeeded with 86 percent efficiency.

The stray tumor cells are known as circulating tumor cells, which are small pieces of a tumor that break away and flow through the bloodstream. They contain information about the tumor, such as its type, physical characteristics and genetic mutations that can help doctors with prognosis and determining the most effective treatments.

The ability to quickly harvest and grow CTCs from a blood sample would enable "liquid biopsies" that could provide a reliable method diagnosis, prognosis and treatment suggestions based on CTC profiling, the researchers say.

"Biopsy is the gold standard technique for cancer diagnosis, but it is painful and invasive and is often not administered until late in the cancer's development," Tony Jun Huang, the William Bevan Professor of Mechanical Engineering and Materials Science at Duke University, said in a press release.

With the team's CTC separation technology, they could find out whether the patient has cancer, where the cancer is located, what stage it's in and which drugs would work best from a small sample of blood instead of invasive surgery, he said.

CTCs are rare and difficult to catch. There are typically only a handful for every few billion blood cells running through a persom's veins, and the many technologies designed to separate them from normal blood cells are flawed. Most damage or kill the cells in the process, lack efficiency, only work on specific types of cancer or take too long to be used in many situations.
[post_ads_2]
The technology works by placing a standing sound wave at an angle to a the fluid flowing through a channel, and the pressure of the sound wave pushes cancer particles in the liquid -- they are larger and more firm than blood cells -- into a separate channel to be collected for analysis.

The sound waves are similar to those in ultrasonic imaging, and there's less risk of damage to the CTCs because each cell experiences the acoustic wave for only a fraction of a second and does not require labeling or surface modification.

The approach was first demonstrated three years ago and has been improved enough to be used in a clinical setting.

With additional improvements to the method, researchers hope the technology will form the basis of a new test through an inexpensive, disposable chip, researchers say.

COMMENTS



Note: If you think this story need more information or correction, feel free to comment below your opinion and reaction.
Like & Follow to Stay Updated ...

Name

Body & Mind,3,Fitness,20,Health,1450,Weight Loss,3,Wellness,2,
ltr
item
Health - U.S. Daily News: Sounds waves may improve liquid biopsies for cancer
Sounds waves may improve liquid biopsies for cancer
https://2.bp.blogspot.com/-ro5DcDpRWEw/W0BVUOwshXI/AAAAAAAAxjg/a-YenK-S9U8M_VqvdZ7VEqc2-Agu6KBxACEwYBhgL/s1600/5.jpg
https://2.bp.blogspot.com/-ro5DcDpRWEw/W0BVUOwshXI/AAAAAAAAxjg/a-YenK-S9U8M_VqvdZ7VEqc2-Agu6KBxACEwYBhgL/s72-c/5.jpg
Health - U.S. Daily News
https://health.dailynews.us.com/2018/07/sounds-waves-may-improve-liquid.html
https://health.dailynews.us.com/
https://health.dailynews.us.com/
https://health.dailynews.us.com/2018/07/sounds-waves-may-improve-liquid.html
true
6734990777582388991
UTF-8
Loaded All Posts Not found any posts VIEW ALL Read More Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share. STEP 2: Click the link you shared to unlock Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy